Armen saghatelyan biography template

Our lab is interested in the understanding of molecular and cellular mechanisms governing adult Neural Stem Cells (NSCs) activation in freely behaving mice, migration and maturation of neuronal precursors and functional integration of new neurons into the mature neuronal circuitry.

Armen saghatelyan biography template

The largest population of NSCs in the adult brain is located  in the subventricular zone (SVZ). Neuronal precursors are generated from NSCs and migrate toward the olfactory bulb (OB) where they integrate into the functional circuitry.

The long-term objective of our research is to identify the molecular and cellular programs orchestrating neuronal development in the adult brain that can be used to build up efficient cell replacement therapies by inducing neuronal recruitment into the brain areas affected by neurodegenerative diseases and brain trauma.

We use multidisciplinary approaches including mini-endoscopic imaging in freely behaving mice, in